Cenforce Information

Cenforce

Brand(s): Cenforce

Manufacturer: Centurion Laboratories Ltd.

Generic name: Sildenafil Citrate

Formula: C28H38N6O11S

Pharmacologic Classifications: Type 5 Inhibitor

Availability: USA, UK, EU, Australia, Canada +

Cenforce Full Review:

Cenforce Review

Cenforce is a branded generic remedy for the treatment of impotence in men due to poor penile erection. It is manufactured by Centurion Laboratories . Cenforce is presented in a strip containing 10 tablets. Each tablet is a white, diamond shaped pill, containing 100mg of Cenforce. Tablets are film coated allowing to achieve a quick effect.

Erectile dysfunction (ED) is a condition when the male isn’t able to maintain the erection long enough for a sexual act. It needs treatment if it happens quite often as ED can affect the relationship and self-esteem of a person. There are many causes of ED like stress, depression, diabetes, hypertension, and kidney disease, injury to the penis or pelvic region.

Centurion Laboratories Information

Cenforce range of products is manufactured by Centurion Laboratories . These products are used for the treatment of erectile dysfunction (ED). Centurion Laboratories is an Indian company specializing in the manufacturing of branded generics.

The company follows high standards in its manufacturing practices to ensure the quality and effectiveness of its brands. It makes sure that all the generics which it manufactures aren’t inferior in quality compared to the brand names.

The company manufactures several branded generics for the treatment of erectile dysfunction. It also manufactures anti infective, hormonal products, and products for use in urology.

As Centurion Laboratories is expanding the list of countries where it is exporting its products, the company fully understands the importance of getting approvals and certifications from various international agencies. As per information on the company’s website, the manufacturing facility of Centurion Laboratories has been approved by the US FDA. The company is continually investing in new technologies to add new value to the end products.

As per Centurion Laboratories website, the company pays high attention to the environmental management. The company recycles all its waste products. There is a very low level of gas and fluid disposed of the units. Centurion Laboratories promotes the planting of trees, and its premises are full of greenery.

Clinical Research on Cenforce 100 mg

Cenforce 100 mg

Cenforce 100 mg has revolutionized the way erectile dysfunction (ED) is treated. Its efficacy and safety have been well established by a great number of studies, carried out using various doses and drug form. Cenforce 100 mg has proved to be a safe and effective treatment of ED for people suffering from diseases like diabetes, hypertension, Parkinsonism.

In the study “Cenforce for male Erectile Dysfunction: A Systematic Review and Meta-analysis” by Howard A. Fink et al, analysis of 27 clinical trials of Cenforce for ED was conducted. These 27 clinical trials were carried out on more than 6000 patients in total. Most patients have been suffering from ED for 3-6 months. 19% of patients were suffering from psychogenic ED, 30% had mixed cause (both psychogenic and organic), and most common comorbidities were hypertension, diabetes, and ischaemic heart disease. Relative to placebo group, Cenforce greatly enhanced erectile function in all sub-groups. At least 83% reported having one successful intercourse during treatment. Most common side effects in the studies were a transient headache, flushing, rhinitis, and dyspepsia. The aim of any therapy is to be reliable, simple and safe. The author of the study concluded that Cenforce has met all these criteria in the analytical study. Though author noted that more long-term trials are needed to establish the efficacy and safety profile of Cenforce.

For most men with ED, the recommended starting dose of Cenforce is 50 mg, but soon most of them have to start taking 100 mg to get an optimal effect from the treatment. Loran OB did clinical study named “Cenforce 100 mg Starting Dose in Men with Erectile Dysfunction in an International, Double-blind, Placebo-controlled Study: Effect on the Sexual Experience and Reducing Feelings of Anxiety about the next Intercourse Attempt” with the dose of 100 mg. In this study, Loran concluded that, though both 50 mg and 100 mg were effective in improving erectile function and decreasing anxiety about the next intercourse, Cenforce at the dose of 100 mg was much more efficient.

There are many short and mid-term studies on Cenforce. During such studies, it was observed that many patients who initially started with 50 mg of Cenforce, later switched on to 100 mg to achieve better erectile function. In the study “Long-Term Efficacy of Cenforce and Tachyphylaxis Effect”, Rizk El-Galley et al tried to find out efficacy and development of resistance to Cenforce when taken over a long time. They followed the group of patients over the period of 2 years. In the study author noted that 17% of patients discontinued therapy due to the loss of efficacy while 20% had to increase the dose of Cenforce to achieve the desirable effect.

Keeping in view the data from different clinical trials, it may be said that for most individuals suffering from ED, 100 mg Cenforce is the most efficient dose form. It is also seen that both film coated tablets and conventional tablets are equally effective for ED. Cenforce tablets have the convenience of using. Numerous clinical studies also show that 100 mg Cenforce is well-tolerated and safe.

Description and Mechanism of Action of Cenforce

Nitric oxide (NO) relaxes penile smooth muscles and also vascular smooth muscles. During sexual stimulation in men, Nitric Oxide is getting released in penile tissues which relax the smooth muscles and results in increased blood movement to the penile tissues, thus leading to an in erection in males.

Cenforce belongs to the class of drugs that inhibit Phosphodiesterase Type 5 enzyme. The inhibition of phosphodiesterase type 5 inhibitors Cenforce extends the duration of NO effect on penile smooth muscles.

Effects of Cenforce

Cenforce tablets of 100 mg are indicated to combat erectile dysfunction. 100 mg Cenforce is considered to be most effective dose and still safe. Doses lower than 100 mg have less clinical success whereas doses above 100 mg have poorer safety profile.

Cenforce can be used in ED or various etiologies, it has shown to be quite effective in treating ED associated with diabetes, hypertension, and cardiac diseases to name a few. Cenforce is highly effective in treating psychogenic ED.

Cenforce has also been useful in the treatment of pulmonary hypertension, but for pulmonary hypertension dose forms are different.

Recommended Doses and Duration of Therapy

In most cases of ED, the recommended dose of Cenforce is 50 mg or 100 mg. 100 mg has been shown as the most effective dose. There are many clinical trials to support the long-term use of Cenforce in ED.

Cenforce should be consumed 1 hour before engaging in sexual intercourse for optimal effect, though it starts working within 30 minutes of intake. It can be either taken with water or without it (chewed and swallowed).

Side Effects and Warnings

Dizziness, flushing of the face, stuffiness of nose, headache, dyspepsia, and blurry vision are most common side effects, though most of these adverse effects don’t last for long.

Serious allergies are possible but rare with the product.

There have been several reports of cardiac side effects in elderly patients, but most of them have been due to the physical stress of sexual activity rather than any direct adverse effect of Cenforce.

Special precaution should be taken by people who have an irregular heartbeat or had an ischemic attack in last six months.

Drug Interactions

Cenforce can cause a drop in blood pressure if taken with nitrates (for, e.g.,. Nitroglycerine). It is not recommended to take Cenforce with them as it may even lead to heart attack or even stroke.

Special care must be exercised when Cenforce is used with alpha-blockers (such as doxazosin, tamsulosin, Fildena) as it may lead to the drop in blood pressure, due to which person may feel dizzy or even faint. It is better to take Cenforce in lowest dose with alpha blockers.

Other medications may interfere with the metabolism of Cenforce. Antifungals, such as ketoconazole, itraconazole, and macrolide antibiotics, such as erythromycin, clarithromycin, may elevate the concentration of Cenforce in the patient’s blood. Hence, a dose correction may be needed.

Customer Reviews

Most of the customers are highly satisfied with the Cenforce. Customers liked that film coated tablets are convenient to use and still there has been no compromise in the quality or potency of strength, which is evident from the remarks of the customers.

One of the previous users of Cenforce James Serrano commented “Consuming ED medicine was never fun earlier. This new chew is just amazing as described here! Great outcome and wonderful prices”.

Cenforce Price, Dosage, and Available Forms

Cenforce comes in a strip and the cost of one strip containing 10 tablets of 100 mg is 34.95 USD. There is a discount if you order more than one strip.

This product can be delivered anywhere in USA, Australia, Canada. Shipping charges of 10$ are added if you order a service of non trackable standard airmail and 30$ if you prefer a trackable courier.

For most people suffering from ED, one tablet of Cenforce 100 mg taken one hour before planned sexual activity will give the desired result.

How to buy Cenforce online

Cenforce is prescription-only medicine. Men who wish to buy Cenforce or other ED medicine online from Cenforce.name must first read medical information about erectile dysfunction and answer medical questions to check for eligibility. Your information is reviewed by our doctors and, if approved, tablets are despatched from our USA pharmacy. All men with ED should consult their doctor before obtaining treatment online.

Buy Cenforce 100 mg, 25 mg, 50 mg, 120 mg, 150 mg, 200 mg, Professional, Cenforce-D, Soft And FM tablets generic drug of sildenafil online at a cheap price from the most trusted Website to cure Erectile Dysfunction. Get all info about this medicine like use, dosage (missed/over), Precautions, Substitutes, the review, how long does the last composition, side effect, manufactured by Centurion Laboratories Pvt. Ltd, how it works, and many more. You can also get speedy delivery in the UK, USA, Australia, Spain, Italy and France.